What is the most frequent complication of Total Parenteral Nutrition (TPN)?

Hyperglycemia. ***Hyperglycemia*** - **Hyperglycemia** is the most common metabolic complication of TPN due to the high dextrose content, especially in patients with pre-existing glucose intolerance or stress. - Close monitoring of blood glucose and insulin administration are often necessary to manage this complication. *Rebound hyperglycemia* - **Rebound hyperglycemia** typically refers to a surge in blood glucose levels following a period of hypoglycemia, or in response to a sudden cessation of insulin, neither of which is the most frequent primary complication of TPN initiation. - While TPN can cause hyperglycemia, the term "rebound hyperglycemia" is not the most accurate description for the initial and most frequent TPN-associated glucose abnormality. *Hypoglycemia* - **Hypoglycemia** is less common during continuous TPN infusion but can occur if TPN is abruptly discontinued, or if excessive insulin is administered. - It is not the most frequent complication observed during steady-state TPN administration. *Hypertriglyceridemia* - **Hypertriglyceridemia** can occur with TPN, particularly with excessive lipid emulsion administration or in patients with impaired lipid metabolism. - Although a potential complication, it is not as frequent as hyperglycemia. [Practice more General Medicine PYQs on OnCourse]

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NEET-PG 2024 — General Medicine

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NEET-PG 2024 General Medicine PYQs | 1+ Solved MCQs – Oncourse AI