Viruses — MCQs

A 27-year-old dental radiographer presented to a clinic with red lesions on his palate, right lower and mid-upper lip, as well as one of his fingers. These lesions were accompanied by slight pain, and the patient had a low-grade fever 1 week before the appearance of the lesions. The patient touched the affected area repeatedly, which resulted in bleeding. Two days prior to his visit, he observed a small vesicular eruption on his right index finger, which merged with other eruptions and became cloudy on the day of the visit. He has not had similar symptoms previously. He did not report drug usage. A Tzanck smear was prepared from scrapings of the aforementioned lesions by the attending physician, and multinucleated epithelial giant cells were observed microscopically. According to the clinical presentation and histologic finding, which viral infection should be suspected in this case?

A 16-year-old male presents to his pediatrician with a sore throat. He reports a severely painful throat preceded by several days of malaise and fatigue. He has a history of seasonal allergies and asthma. The patient is a high school student and is on the school wrestling team. He takes cetirizine and albuterol. His temperature is 100.9°F (38.3°C), blood pressure is 100/70 mmHg, pulse is 100/min, and respirations are 20/min. Physical examination reveals splenomegaly and posterior cervical lymphadenopathy. Laboratory analysis reveals the following: Serum: Na+: 145 mEq/L K+: 4.0 mEq/L Cl-: 100 mEq/L HCO3-: 24 mEq/L BUN: 12 mg/dL Ca2+: 10.2 mg/dL Mg2+: 2.0 mEq/L Creatinine: 1.0 mg/dL Glucose: 77 mg/dL Hemoglobin: 17 g/dL Hematocrit: 47% Mean corpuscular volume: 90 µm3 Reticulocyte count: 1.0% Platelet count: 250,000/mm3 Leukocyte count: 13,000/mm3 Neutrophil: 45% Lymphocyte: 42% Monocyte: 12% Eosinophil: 1% Basophil: 0% Which of the following cell surface markers is bound by the pathogen responsible for this patient’s condition?

A 15-month-old girl is brought to the physician because of a 2-day history of low-grade fever and a painful lesion on her right index finger. She was born at term and has been healthy except for a rash on her upper lip 2 weeks ago, which resolved without treatment. She lives at home with her parents, her 5-year-old brother, and two cats. Her temperature is 38.5°C (101.3°F), pulse is 110/min, respirations are 30/min, and blood pressure is 100/70 mm Hg. A photograph of the right index finger is shown. Physical examination shows tender left epitrochlear lymphadenopathy. Which of the following is the most likely causal organism?

A previously healthy 16-year-old girl comes to the physician because of fever, fatigue, and a sore throat for 8 days. She also has a diffuse rash that started yesterday. Three days ago, she took amoxicillin that she had at home. She is sexually active with two male partners and uses condoms inconsistently. Her temperature is 38.4°C (101.1°F), pulse 99/min, blood pressure 106/70 mm Hg. Examination shows a morbilliform rash over her trunk and extremities. Oropharyngeal examination shows tonsillar enlargement and erythema with exudates. Tender cervical and inguinal lymphadenopathy are present. Abdominal examination shows mild splenomegaly. A peripheral blood smear shows lymphocytosis with > 10% atypical lymphocytes. Which of the following is most likely to be positive in this patient?

A 36-year-old woman presents to the emergency department with a 2-day history of conjunctivitis, sensitivity to bright light, and decreased visual acuity. She denies a history of ocular trauma. She wears contact lenses and thought that the contact lenses may be the cause of the symptoms, although she has always used proper hygiene. Fluorescein staining showed a corneal dendritic branching ulcer with terminal bulbs that stained with rose bengal. Giemsa staining revealed multinucleated giant cells. What is the most likely causative agent?