NEET-PG 2013 Practice Questions

Q: In the context of triage, what color would be assigned to a moribund patient?

Black. ***Black*** - A **black tag** is assigned to patients who are **deceased** or have injuries so severe that survival is unlikely, and resources would be better used on patients with a higher chance of survival. - A **moribund patient** is in a dying state or near death, fitting the criteria for a black tag in triage. *Red* - **Red tags** are for patients with **immediate life-threatening injuries** who have a high probability of survival with prompt intervention. - These patients require immediate medical attention to stabilize fundamental physiological functions. *Yellow* - **Yellow tags** are assigned to patients with **serious injuries** that are not immediately life-threatening. - They require medical attention within a few hours, but their condition is stable enough to wait after red-tagged patients. *Green* - **Green tags** are for patients with **minor injuries** that are non-life-threatening and can wait for medical attention. - These individuals are often referred to as "walking wounded" and can typically care for themselves or assist others.

Q: What is the most common cause of ASOM?

Pneumococci. ***Pneumococci*** - **_Streptococcus pneumoniae_ (Pneumococci)** is the **most common bacterial cause** of Acute Suppurative Otitis Media (ASOM) in all age groups, particularly in young children. - It accounts for an estimated 25-50% of all ASOM cases, often leading to significant inflammation and **purulent discharge**. *Meningococci* - **_Neisseria meningitidis_ (Meningococci)** is rarely a cause of ASOM. - It is primarily known for causing **meningitis** and **sepsis**, not typically middle ear infections. *H. influenzae* - **_Haemophilus influenzae_ (non-typable)** is the **second most common cause** of ASOM, accounting for 20-40% of cases. - While significant, it is generally less prevalent than _Streptococcus pneumoniae_. *Moraxella catarrhalis* - **_Moraxella catarrhalis_** is another common causative agent of ASOM, responsible for 10-20% of cases. - It is frequently seen in conjunction with other pathogens but is not the most common on its own.

Q: What is the penalty for violating the Dowry Prohibition Act?

15000 Rs and 5 years. ***15000 Rs and 5 years*** - The **Dowry Prohibition Act of 1961** (as amended) stipulates that any person giving or taking dowry, or abetting the giving or taking of dowry, shall be punishable with imprisonment for a term which shall **not be less than five years** and with a fine which shall **not be less than fifteen thousand rupees** or the amount of the value of such dowry, whichever is more. - This represents the **minimum prescribed penalty** for offenses under Section 3 of the Act. *30000 Rs and 7 years* - While dowry-related offenses can lead to significant penalties, a flat fine of **30,000 Rs** and an imprisonment of **7 years** is not the standard or minimum penalty outlined in the **Dowry Prohibition Act**. - The minimum fine is **15,000 Rs or the dowry amount, whichever is more**, and the minimum imprisonment is **five years**, not seven. *Life imprisonment* - **Life imprisonment** is typically reserved for very severe crimes, and while dowry-related deaths can lead to such severe penalties under **Section 304B IPC for dowry death**, violating the general provisions of the **Dowry Prohibition Act** itself (giving or taking dowry under Section 3) does not directly carry a penalty of life imprisonment. - This option misrepresents the direct penalty for dowry prohibition violations under the Act. *Imprisonment for 10 years* - Imprisonment for **10 years** is not the prescribed minimum or standard penalty for violating the **Dowry Prohibition Act** under Section 3 for giving or taking dowry. - The **minimum imprisonment is five years**, with potential for longer sentences depending on the specific circumstances and judicial discretion.

Q: Which of the following is a cause of Valley fever (desert rheumatism)?

Coccidioides. ***Coccidioides*** - **Valley fever**, or desert rheumatism, is caused by infection with the dimorphic fungus **Coccidioides**, primarily **Coccidioides immitis** and **Coccidioides posadasii**. - This fungus is endemic to arid and semi-arid regions, especially the **southwestern United States** and parts of Central and South America. *Sporothrix* - **Sporothrix schenckii** causes sporotrichosis, a chronic fungal infection typically involving the skin, subcutaneous tissue, and adjacent lymphatics, often through skin trauma. - It does not cause Valley fever. *Cladosporium* - **Cladosporium** species are ubiquitous molds commonly found in outdoor and indoor environments, often associated with allergic reactions and occasionally superficial infections. - They are not a cause of Valley fever. *Phialophora* - **Phialophora** species are dematiaceous fungi that can cause phaeohyphomycosis, chromoblastomycosis, and eumycetoma, which are subcutaneous or systemic fungal infections. - They are not associated with Valley fever.

Q: Who discovered the bacterium Mycobacterium tuberculosis, which causes tuberculosis?

Robert Koch. ***Robert Koch*** - **Robert Koch** discovered the bacterium *Mycobacterium tuberculosis* in **1882**, identifying its role as the causative agent of tuberculosis. - His work was crucial in establishing the germ theory of disease and earned him the Nobel Prize in Physiology or Medicine in 1905. *Louis Pasteur* - **Louis Pasteur** was a pioneer in microbiology, known for his work on **pasteurization**, **vaccinations** (e.g., rabies and anthrax), and disproving spontaneous generation. - While he made significant contributions to understanding infectious diseases, he did not discover *Mycobacterium tuberculosis*. *Lister* - **Joseph Lister** was a British surgeon who revolutionized surgery by introducing **antiseptic techniques** using carbolic acid to prevent infections. - His contributions were fundamental to reducing mortality rates from surgical infections, but he did not discover the tuberculosis bacterium. *Jenner* - **Edward Jenner** is famous for developing the **smallpox vaccine**, which was a groundbreaking achievement in immunology and public health. - His work, though vital for preventing infectious diseases, predates and is unrelated to the discovery of *Mycobacterium tuberculosis*.

Q: Which of the following is an intermediate level disinfectant?

Hypochlorite. ***Hypochlorite*** - **Hypochlorite** (e.g., sodium hypochlorite, bleach) is an effective **intermediate-level disinfectant** commonly used for surface disinfection and water purification. - It works by **oxidizing cellular components** and disrupting membrane function in microorganisms, effective against a wide range of bacteria, viruses, and some fungi. *2% glutaraldehyde* - **2% glutaraldehyde** is a **high-level disinfectant** and **sterilant** often used for heat-sensitive medical equipment like endoscopes. - It is effective against bacterial spores, mycobacteria, fungi, and viruses, which exceeds the scope of intermediate-level disinfection. *Ethylene oxide* - **Ethylene oxide** is a **gaseous sterilant** used for heat-sensitive and moisture-sensitive medical devices, making it a high-level modality. - It works by **alkylating proteins and nucleic acids**, effectively killing all forms of microbial life, including spores. *None of the options* - This option is incorrect because **Hypochlorite** is indeed an intermediate-level disinfectant. - The classification of disinfectants is based on their ability to kill different types of microorganisms, with hypochlorite falling squarely into the intermediate category.

Q: Ranibizumab is a monoclonal antibody against?

VEGF. ***VEGF*** - **Ranibizumab** is a **monoclonal antibody** specifically designed to inhibit **vascular endothelial growth factor A (VEGF-A)**. - By binding to VEGF-A, ranibizumab prevents its interaction with receptors on endothelial cells, thereby inhibiting **angiogenesis** and reducing vascular permeability, which is crucial in treating conditions like **wet age-related macular degeneration (AMD)** and **diabetic macular edema**. *Interleukin-6* - **Interleukin-6 (IL-6)** is a **pro-inflammatory cytokine** involved in various autoimmune and inflammatory diseases. - Monoclonal antibodies targeting IL-6, such as **tocilizumab**, are used in conditions like **rheumatoid arthritis** and **cytokine release syndrome**, not for ocular neovascularization. *Cluster of Differentiation 20* - **Cluster of Differentiation 20 (CD20)** is a protein found on the surface of **B lymphocytes**. - Monoclonal antibodies against CD20, like **rituximab**, are used in the treatment of **B-cell lymphomas**, **leukemia**, and certain **autoimmune diseases**, not for conditions requiring anti-VEGF therapy. *Epidermal Growth Factor Receptor* - The **epidermal growth factor receptor (EGFR)** is a **tyrosine kinase receptor** involved in cell growth and proliferation. - Monoclonal antibodies targeting EGFR, such as **cetuximab** and **panitumumab**, are used in the treatment of various **cancers**, particularly **colorectal cancer** and **head and neck cancer**.

Q: Nesiritide causes vasodilation through?

Guanosine 3',5'-cyclic monophosphate (cGMP). ***Guanosine 3',5'-cyclic monophosphate (cGMP)*** - **Nesiritide** is a synthetic **B-type natriuretic peptide (BNP)** that acts as a potent vasodilator [2]. - It works by binding to **guanylyl cyclase receptors**, leading to an increase in intracellular **cGMP**, which promotes smooth muscle relaxation [1], [2]. *Cyclic adenosine monophosphate (cAMP)* - While **cAMP** is a crucial second messenger in various cellular processes and can mediate some forms of vasodilation, it is primarily associated with **beta-adrenergic receptor activation**, not the mechanism of action of nesiritide. - Nesiritide's pathway is distinct from those involving **cAMP-mediated** relaxation, which often involves different kinases and protein phosphorylation. *ATP* - **ATP** (adenosine triphosphate) is the primary **energy currency** of the cell and is involved in numerous cellular functions, including muscle contraction and relaxation, but it is not a direct mediator of nesiritide's vasodilatory effects. - Though ATP can be broken down to produce **adenosine**, which has vasodilatory properties, this is not the specific mechanism through which nesiritide causes vasodilation. *K+ ions* - Changes in **potassium ion (K+)** flux across cell membranes are essential for regulating vascular tone, as K+ channel activation can lead to hyperpolarization and relaxation of smooth muscle. - However, **nesiritide's primary mechanism** of action does not involve direct modulation of K+ channels; its vasodilatory effects are mediated by the **cGMP pathway** [2].

Q: Botulinum toxin acts on

Synapse. ***Synapse*** - **Botulinum toxin** acts by inhibiting the release of **acetylcholine** at the **neuromuscular junction**, which is a type of synapse. - This blockade of neurotransmitter release at the **presynaptic terminal** prevents muscle contraction, leading to paralysis. *Smooth muscle of intestine* - While botulinum toxin can affect smooth muscle indirectly by paralyzing the motor nerves innervating them, its primary site of action is the **synapse** itself, not directly on the muscle fibers. - The toxin primarily targets the nerve endings, rather than the mechanical contractility of the muscle cell. *Central nervous system* - **Botulinum toxin** does not readily cross the **blood-brain barrier**, meaning its primary effects are peripheral. - Its therapeutic and toxic effects are localized to the **peripheral nervous system** and neuromuscular junctions. *Sensory nerves* - **Botulinum toxin** specifically targets **motor nerve endings** to inhibit acetylcholine release, leading to muscle paralysis. - It does not directly affect the function of **sensory nerve transmission** or pain perception in the same way.

Q: Most common organ involved in air blast injury is?

Ear drum. ***Ear drum*** - The **tympanic membrane (eardrum)** is highly sensitive to changes in pressure, making it the most vulnerable and frequently injured organ during **air blast events**. - Its delicate structure can easily rupture due to the sudden, immense pressure wave. *Stomach* - While blast injuries can affect the gastrointestinal tract, causing conditions like **bowel perforation**, the stomach is less commonly and directly impacted than the eardrum. - Gastrointestinal injury usually results from a combination of **blast waves** and secondary effects like **fragmentation**. *Eye* - Eye injuries from blasts often involve **foreign bodies**, **ocular trauma**, or **thermal burns**, but direct **barotrauma** to the eye itself is less common than eardrum rupture. - The eye is somewhat protected by the bony orbit, offering a degree of shielding from direct blast effects. *Lung* - **Blast lung injury** is a serious, life-threatening condition involving pulmonary contusions, hemorrhage, and rupture of alveoli. - While significant, it is generally considered less frequent than eardrum perforation in overall blast injury cases.

Question 1

In the context of triage, what color would be assigned to a moribund patient?

Accepted Answer

Black

Answer

Red

Answer

Yellow

Answer

Green

Question 2

What is the most common cause of ASOM?

Accepted Answer

Pneumococci

Answer

Meningococci

Answer

H. influenzae

Answer

Moraxella catarrhalis

Question 3

What is the penalty for violating the Dowry Prohibition Act?

Accepted Answer

15000 Rs and 5 years

Answer

30000 Rs and 7 years

Answer

Life imprisonment

Answer

Imprisonment for 10 years

Question 4

Which of the following is a cause of Valley fever (desert rheumatism)?

Accepted Answer

Coccidioides

Answer

Sporothrix

Answer

Cladosporium

Answer

Phialophora

Question 5

Who discovered the bacterium Mycobacterium tuberculosis, which causes tuberculosis?

Accepted Answer

Robert Koch

Answer

Jenner

Answer

Louis Pasteur

Answer

Lister

Question 6

Which of the following is an intermediate level disinfectant?

Accepted Answer

Hypochlorite

Answer

Ethylene oxide

Answer

2% glutaraldehyde

Answer

None of the options

Question 7

Ranibizumab is a monoclonal antibody against?

Accepted Answer

VEGF

Answer

Interleukin-6

Answer

Cluster of Differentiation 20

Answer

Epidermal Growth Factor Receptor

Question 8

Nesiritide causes vasodilation through?

Accepted Answer

Guanosine 3',5'-cyclic monophosphate (cGMP)

Answer

ATP

Answer

Cyclic adenosine monophosphate (cAMP)

Answer

K+ ions

Question 9

Botulinum toxin acts on

Accepted Answer

Synapse

Answer

Smooth muscle of intestine

Answer

Central nervous system

Answer

Sensory nerves

Question 10

Most common organ involved in air blast injury is?

Accepted Answer

Ear drum

Answer

Stomach

Answer

Eye

Answer

Lung

NEET-PG 2013

Community Medicine

ENT

Forensic Medicine

Microbiology

Pharmacology

Surgery