NEET-PG 2013 Practice Questions

Q: Which drug is commonly used for emergency intubation?

Etomidate. ***Etomidate*** - Etomidate is a **short-acting nonbenzodiazepine hypnotic** often preferred for rapid sequence intubation (RSI) due to its minimal impact on **hemodynamic stability**. - It induces **rapid unconsciousness** with a quick onset and offset, making it suitable for emergency airway management in patients who are hemodynamically compromised. *Propofol* - Propofol is a **potent intravenous anesthetic** that can cause significant **hypotension** due to vasodilation and myocardial depression. - While it provides rapid onset of sedation and amnesia, its cardiovascular side effects make it less ideal for patients with **unstable hemodynamics** during emergency intubation. *Ketamine* - Ketamine is a **dissociative anesthetic** that causes a cataleptic state, amnesia, and analgesia, often leading to **bronchodilation** and cardiovascular stimulation. - While useful in patients with **reactive airway disease** or hypotension, it can increase intracranial pressure and may induce sympathetic stimulation, which might not be ideal for all emergency intubation scenarios. *None of the options* - This option is incorrect because **Etomidate is a commonly used drug** for emergency intubation, particularly where hemodynamic stability is a concern. - Other agents are also used but Etomidate is a clear clinical choice in many situations.

Q: Dissociative anaesthesia is produced by?

Ketamine. ***Ketamine*** - **Ketamine** is a unique anesthetic that produces a state of **dissociative anesthesia**, characterized by a trance-like state, analgesia, amnesia, and catalepsy. - This effect is primarily due to its antagonism of the **N-methyl-D-aspartate (NMDA) receptor**. *Etomidate* - **Etomidate** is an intravenous anesthetic characterized by its **cardiovascular stability**, making it suitable for patients with heart conditions. - It works primarily by modulating **GABA-A receptors** but does not produce dissociative anesthesia. *Propofol* - **Propofol** is a widely used intravenous anesthetic known for its **rapid onset and recovery**, and it is often used for induction and maintenance of general anesthesia. - Its primary mechanism of action involves enhancing the effects of **GABA-A receptors**, leading to central nervous system depression, but not dissociative anesthesia. *Thiopentone* - **Thiopentone** (Thiopental) is a barbiturate anesthetic that causes rapid loss of consciousness and has been historically used for inducing general anesthesia. - It acts as a **GABA-A receptor agonist**, depressing the central nervous system, but it does not produce the distinct dissociative state seen with ketamine.

Q: What is the primary maternal cause of fetal macrosomia (large birth weight) in newborns?

Hyperglycemia. ***Hyperglycemia*** - Maternal **hyperglycemia**, often due to **gestational diabetes**, leads to increased glucose transfer across the placenta to the fetus. - This excess glucose stimulates increased fetal insulin production, which acts as a growth hormone causing macrosomia. *Hyperinsulinemia* - While fetal **hyperinsulinemia** directly causes macrosomia by increasing fetal growth, it is a **consequence** of maternal hyperglycemia, not the primary cause itself. - Fetal insulin acts as an anabolic hormone, promoting fat and protein synthesis and overall growth. *Multiparity* - **Multiparity** (having given birth to multiple children) is generally associated with moderately higher birth weights, but it is not the primary cause of macrosomia. - The effect is far less significant and consistent than that of maternal hyperglycemia. *Post maturity* - **Post-term pregnancy** (post maturity) can sometimes be associated with a larger birth weight, but this is less common and less pronounced than macrosomia caused by hyperglycemia. - Fetal growth often slows or even declines in prolonged pregnancies due to placental insufficiency.

Q: What is the recommended timing for the insertion of a Copper T intrauterine device?

Within 10 days of start of menstrual cycle. ***Within 10 days of start of menstrual cycle*** - Inserting the **Copper T IUD** during this phase ensures the woman is not pregnant, as ovulation typically occurs later in the cycle. - The **cervix is slightly dilated** during menstruation, making insertion easier and less uncomfortable. - This is the **recommended timing** as per standard guidelines for IUD insertion. *3 days after periods are over* - While this timing might seem appropriate, it doesn't align with the optimal window for ensuring **non-pregnancy** and ease of insertion. - The **cervix may have already closed** significantly, making insertion potentially more difficult than during menstruation. *During active pelvic infection* - Insertion of an IUD during an **active pelvic infection** is **absolutely contraindicated** due to the risk of exacerbating the infection and leading to more serious complications like **pelvic inflammatory disease (PID)**. - The presence of infection increases the likelihood of bacteria being carried into the **uterine cavity**, potentially causing severe consequences. *Just after menstruation* - While close to the ideal window, this timing is less specific than "within 10 days" and may miss the optimal cervical conditions. - The benefits of a slightly dilated cervix during the early menstrual phase would be maximized with the more precise timing of within 10 days of cycle start.

Q: What is the purpose of the Insall-Salvati index?

To assess patellar height and tendon length ratio. ***To assess patellar height and tendon length ratio*** - The **Insall-Salvati index** is a radiographic measurement used to determine **patellar height** by comparing the length of the patellar tendon to the greatest diagonal length of the patella. - It helps in diagnosing conditions like **patella alta** (high-riding patella) or **patella baja** (low-riding patella), which can contribute to knee pain and instability. *To evaluate elbow joint stability* - **Elbow joint stability** is typically assessed through clinical examination for ligamentous integrity (e.g., UCL, RCL) and sometimes dynamic imaging, not by the Insall-Salvati index. - The Insall-Salvati index is specific to the **knee joint** and **patellar position**. *To measure ankle dorsiflexion range* - **Ankle dorsiflexion range** is measured clinically using a goniometer or in 3D motion analysis, not with the Insall-Salvati index. - This index is a specialized measurement for the **patellofemoral joint**. *To assess wrist bone alignment* - **Wrist bone alignment** is evaluated using various radiographic measurements such as the scaphoid-lunate angle or carpal height ratio. - The Insall-Salvati index has no application in the assessment of the **wrist**.

Q: Most common site of osteochondritis dissecans?

Lateral part of the medial femoral condyle. ***Lateral part of the medial femoral condyle*** - This is the **most common site** for osteochondritis dissecans in the knee, accounting for about 85% of cases. - The condition involves a localized area of **osteonecrosis and subchondral bone separation** from the epiphysis, typically afflicting this specific load-bearing region. *Medial part of the medial femoral condyle* - This location is **less common** for osteochondritis dissecans compared to the lateral aspect of the medial femoral condyle. - While osteochondral lesions can occur on any part of the condyle, the specific biomechanical stresses make the lateral part more susceptible. *Lateral part of the lateral femoral condyle* - Osteochondritis dissecans is **rarely found** in this location. - The lateral femoral condyle is generally less involved in osteochondritis dissecans of the knee. *Medial part of the lateral femoral condyle* - This site is also an **uncommon location** for osteochondritis dissecans. - The disease has a strong predilection for the medial femoral condyle, particularly its lateral aspect.

Q: In pseudocholinesterase deficiency, which drug should be used cautiously?

Succinylcholine. ***Succinylcholine*** - **Succinylcholine** is primarily metabolized by **pseudocholinesterase** (also known as butyrylcholinesterase). - In individuals with **pseudocholinesterase deficiency**, the metabolism of succinylcholine is significantly delayed, leading to **prolonged neuromuscular blockade** and extended paralysis. *Barbiturates* - **Barbiturates** are mainly metabolized by the **hepatic cytochrome P450 system** and do not depend on pseudocholinesterase for their breakdown. - Their metabolism would not be significantly affected by pseudocholinesterase deficiency. *Halothane (an inhalational anesthetic)* - **Halothane** is primarily metabolized by the **hepatic cytochrome P450 system** and excreted via the lungs. - Its metabolism is unrelated to **pseudocholinesterase activity**. *Gallamine (a neuromuscular blocker)* - **Gallamine** is a **nondepolarizing neuromuscular blocker** that is primarily eliminated by **renal excretion** as an unchanged drug. - Its metabolism and elimination are independent of **pseudocholinesterase**.

Q: Astasia-abasia is associated with which of the following conditions?

Functional Neurological Symptom Disorder. ***Functional Neurological Symptom Disorder*** - **Astasia-abasia**, which refers to an inability to stand (astasia) and walk (abasia) despite normal motor function when examined in bed, is a classical presentation of **Functional Neurological Symptom Disorder** (formerly conversion disorder). - This disorder involves neurological symptoms that are incompatible with recognized medical conditions and often linked to **psychological stressors**. - The gait disturbance is bizarre and inconsistent with any known neurological pattern. *Post-Traumatic Stress Disorder* - Characterized by re-experiencing a **traumatic event**, avoidance behaviors, negative alterations in cognitions and mood, and hyperarousal. - While it can manifest with physical symptoms, **astasia-abasia** is not a primary or characteristic feature. *Depressive Disorder* - Primarily involves persistent **sadness**, loss of interest or pleasure, changes in appetite or sleep, and feelings of worthlessness or guilt. - Although physical symptoms like fatigue and psychomotor retardation can occur, **astasia-abasia** is not a typical presentation. *Bipolar Mood Disorder* - Distinguished by episodes of both **mania** (or hypomania) and **depression**. - Symptoms are predominantly mood-related, including extreme shifts in energy, activity levels, and concentration, not specific neurological deficits like astasia-abasia.

Q: "String of beads" appearance on horizontal abdominal view X-ray is suggestive of:

Small bowel obstruction. ***Small bowel obstruction*** - A "string of beads" appearance on a horizontal abdominal view X-ray refers to small gas bubbles trapped between the valvulae conniventes in a dilated small bowel loop. - This finding is highly suggestive of **complete small bowel obstruction**, particularly when accompanied by multiple air-fluid levels and dilated bowel loops. *Intussusception* - While it causes obstruction, intussusception usually appears as a **target sign** (doughnut sign) on ultrasound or a **meniscus sign** on barium enema, not a string of beads on plain X-ray. - Plain X-rays may show signs of **bowel obstruction**, but the string of beads is not characteristic. *Sigmoid volvulus* - Sigmoid volvulus is characterized by a **dilated loop of colon** forming an inverted U-shape, often described as a **coffee bean sign** or **omega sign**, on plain X-ray. - This involves the large bowel, and the "string of beads" specifically relates to gas in the small bowel. *Large bowel obstruction* - Large bowel obstruction typically presents with a **dilated colon** proximal to the obstruction and a collapsed distal colon, often with absent or minimal gas in the rectum and sigmoid. - While air-fluid levels can be present, the "string of beads" is a specific sign of gas within dilated small bowel loops, distinguishing it from most large bowel obstructions.

Q: Which condition is associated with the pencil in cup deformity?

Psoriatic arthritis. ***Psoriatic arthritis*** - The **pencil-in-cup deformity** is a classic radiographic finding in advanced psoriatic arthritis, occurring due to **periarticular bone erosion** and phalangeal telescoping. - This specific deformity is characterized by the proximal phalanx eroding and fitting into the expanded distal phalanx, resembling a "pencil in a cup." *Rheumatoid arthritis* - While rheumatoid arthritis causes significant joint destruction, it typically presents with **periarticular erosions** and **joint space narrowing**, but not the characteristic pencil-in-cup morphology. - Common deformities include **swan-neck** and **boutonnière** deformities, and ulnar deviation. *Ankylosing spondylitis* - This condition primarily affects the **axial skeleton**, leading to spinal fusion and **sacroiliitis**. - Peripheral joint involvement is less common and typically does not result in the pencil-in-cup deformity; instead, it can cause **syndesmophytes**. *Avascular necrosis* - **Avascular necrosis** (AVN) involves the death of bone tissue due to lack of blood supply, primarily affecting the femoral head or other major joints. - Radiographic findings include **subchondral collapse**, crescent sign, and eventual joint destruction, but not the specific deformities seen in inflammatory arthritis like pencil-in-cup.

Question 1

Which drug is commonly used for emergency intubation?

Accepted Answer

Etomidate

Answer

None of the options

Answer

Propofol

Answer

Ketamine

Question 2

Dissociative anaesthesia is produced by?

Accepted Answer

Ketamine

Answer

Etomidate

Answer

Propofol

Answer

Thiopentone

Question 3

What is the primary maternal cause of fetal macrosomia (large birth weight) in newborns?

Accepted Answer

Hyperglycemia

Answer

Hyperinsulinemia

Answer

Multiparity

Answer

Post maturity

Question 4

What is the recommended timing for the insertion of a Copper T intrauterine device?

Accepted Answer

Within 10 days of start of menstrual cycle

Answer

3 days after periods are over

Answer

Just after menstruation

Answer

During active pelvic infection

Question 5

What is the purpose of the Insall-Salvati index?

Accepted Answer

To assess patellar height and tendon length ratio

Answer

To measure ankle dorsiflexion range

Answer

To evaluate elbow joint stability

Answer

To assess wrist bone alignment

Question 6

Most common site of osteochondritis dissecans?

Accepted Answer

Lateral part of the medial femoral condyle

Answer

Medial part of the medial femoral condyle

Answer

Lateral part of the lateral femoral condyle

Answer

Medial part of the lateral femoral condyle

Question 7

In pseudocholinesterase deficiency, which drug should be used cautiously?

Accepted Answer

Succinylcholine

Answer

Barbiturates

Answer

Gallamine

Answer

Halothane

Question 8

Astasia-abasia is associated with which of the following conditions?

Accepted Answer

Functional Neurological Symptom Disorder

Answer

Post-Traumatic Stress Disorder

Answer

Depressive Disorder

Answer

Bipolar Mood Disorder

Question 9

"String of beads" appearance on horizontal abdominal view X-ray is suggestive of:

Accepted Answer

Small bowel obstruction

Answer

Intussusception

Answer

Sigmoid volvulus

Answer

Large bowel obstruction

Question 10

Which condition is associated with the pencil in cup deformity?

Accepted Answer

Psoriatic arthritis

Answer

Rheumatoid arthritis

Answer

Ankylosing spondylitis

Answer

Avascular necrosis

NEET-PG 2013

Anesthesiology

Obstetrics and Gynecology

Orthopaedics

Pharmacology

Psychiatry

Radiology