Question 1

Q: Most common cause of neuropathic joint is:

Diabetes mellitus. ***Diabetes mellitus*** - **Peripheral neuropathy** is a common complication of diabetes, leading to loss of protective sensation and proprioception in the joints [1]. - This sensory loss, combined with repetitive microtrauma, is the most frequent cause of **Charcot arthropathy (neuropathic joint)** in developed countries [1]. *Amyloidosis (systemic amyloidosis)* - While amyloidosis can cause **neuropathy**, it is a far less common cause of neuropathic joint compared to diabetes. - **Amyloid deposition** can directly affect joints but typically presents as an inflammatory or erosive arthropathy rather than classic neuropathic destruction. *Leprosy (Hansen's disease)* - **Leprosy** can cause significant peripheral neuropathy, leading to neuropathic changes, particularly in the feet and hands. - However, due to its **rarity in many parts of the world** and effective treatment, it is not the most common cause globally. *Syphilis (neurosyphilis)* - **Tabes dorsalis**, a late manifestation of neurosyphilis, can cause severe proprioceptive loss and lead to **Charcot joints**, particularly in the knees and hips. - With the advent of antibiotics, **neurosyphilis** is now a very rare cause of neuropathic joint compared to diabetes.

Question

Most common cause of neuropathic joint is:

Accepted Answer

Diabetes mellitus

Answer

Amyloidosis (systemic amyloidosis)

Answer

Leprosy (Hansen's disease)

Answer

Syphilis (neurosyphilis)

Arthrology and Infections — MCQs

Arthrology and Infections — MCQs

On this page

Practice by Chapter

Want unlimited practice?