Population Genetics in Forensics Practice Questions

Question 1

Which of the following techniques can be used to detect single base pair substitutions?

Accepted Answer

PCR

Answer

FISH

Answer

Southern blot

Answer

Restriction Fragment Length Polymorphism (RFLP)

Question 2

The fundamental equilibrium principle of population genetics was given by?

Accepted Answer

Hardy Weinberg

Answer

Sewall Wright

Answer

J. B. S. Haldane

Answer

R. A. Fisher

Question 3

Which of the following is a stochastic effect of radiation?

Accepted Answer

Genetic mutation

Answer

Alopecia in the irradiated portal

Answer

Local desquamation in the irradiated field

Answer

All of the options

Question 4

DNA fingerprinting was discovered by:

Accepted Answer

Jeffreys

Answer

Galton

Answer

Crick

Answer

Southern

Question 5

DNA fingerprinting is used for paternity testing and forensic identification of suspects. Which of the following is the most accurate description of DNA fingerprinting?

Accepted Answer

DNA can be isolated from blood, skin, or sperm and analyzed for variable patterns of restriction fragments arising from tandemly repeated sequences (microsatellites)

Answer

DNA is isolated from blood, skin, or sperm and its fragment size distribution is analyzed by gel electrophoresis

Answer

DNA is isolated from blood, skin, or sperm and hybridized with probes from the HLA locus to visualize HLA gene patterns

Answer

DNA is copied from blood, skin, or sperm RNA using reverse transcriptase and analyzed for the pattern of complementary DNAs

Question 6

Which of the following fields is primarily associated with the Hardy-Weinberg law?

Accepted Answer

Population genetics

Answer

Health economics

Answer

Social medicine

Answer

Epidemiology

Question 7

Which among the following is the best sample for DNA in advanced burnt dead body?

Accepted Answer

Femur

Answer

Spleen

Answer

Enamel

Answer

Sternum

Question 8

DNA matching used for identification and comparison among family members is based on analysis of which genetic marker?

Accepted Answer

Short tandem repeats (STRs)

Answer

Single nucleotide polymorphisms (SNPs)

Answer

Ribosomal RNA genes

Answer

Mitochondrial DNA

Question 9

What is the underlying principle of using mitochondrial DNA rather than nuclear DNA for identification in severely degraded disaster victim remains?

Accepted Answer

Mitochondrial DNA is present in thousands of copies per cell making it more likely to be recovered

Answer

Mitochondrial DNA is more specific for individual identification

Answer

Mitochondrial DNA is not affected by environmental factors

Answer

Mitochondrial DNA analysis is less expensive and faster

Question 10

Absolute proof of monozygosity is determined by?

Accepted Answer

DNA fingerprinting

Answer

Intervening membrane layers

Answer

Sex of the babies

Answer

Reciprocal skin grafting

Population Genetics in Forensics — MCQs

Population Genetics in Forensics — MCQs

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