NEET-PG 2015 Practice Questions

Q: Japanese encephalitis vaccine in routine schedule is given in how many doses -

Two doses (at 9-12 months and 15-18 months). ***Two doses (at 9-12 months and 15-18 months)*** - The **routine JE vaccination schedule in India** as per NTAGI and IAP recommendations involves **two doses**. - **First dose** is given at **9-12 months** of age. - **Second dose** is administered at **15-18 months** (or up to 24 months), approximately **6-12 months after the first dose**. - This provides adequate long-term protection against Japanese encephalitis in endemic areas. *Single dose vaccine* - A single dose does **not provide adequate long-lasting protection** against Japanese encephalitis. - The **immune response** from a single dose is insufficient for routine immunization. - Two doses are required to ensure protective antibody levels. *Three doses 1 month apart followed by a booster if needed* - This schedule is **not part of the routine immunization program** for JE in India. - The standard routine schedule involves **only 2 primary doses**, not three. - Rapid three-dose schedules may be used in specific outbreak situations but not for routine immunization. *Three doses with the second dose 1 month and 3rd dose 6 months after the first dose* - This three-dose schedule is **not the routine JE vaccination schedule** in India. - This may be confused with schedules for other vaccines or older JE vaccine protocols. - The current **routine schedule requires only 2 doses** at specified age intervals.

Q: Reduced osmolarity ORS does not contain which of the following ions?

Lactate. ***Lactate*** - The **reduced osmolarity ORS** formulation replaced **bicarbonate** with **citrate** and does not contain lactate. - **Citrate** is preferred over lactate / bicarbonate due to its stability, longer shelf life, and ease of dissolution. *Sodium* - **Sodium** is a crucial component of ORS, as it is co-transported with glucose into enterocytes, facilitating water absorption through **solvent drag**. - Reduced osmolarity ORS has a **lower sodium concentration** (75 mEq/L) compared to standard ORS (90 mEq/L) to minimize hypernatremia risk and enhance water absorption. *Potassium* - **Potassium** is included in ORS to replace intestinal losses, as **diarrhea** leads to significant potassium depletion. - Maintaining adequate **potassium levels** is essential for normal cellular function and preventing hypokalemia-related complications. *Citrate* - **Citrate** is a component of ORS that serves as an **alkalinizing agent** to correct metabolic acidosis often associated with dehydration in diarrheal diseases. - It also enhances the absorption of sodium and water in the intestine.

Q: What condition is suggested by eyelid papules and a hoarse cry in a child?

Lipoid proteinosis. ***Lipoid proteinosis*** - This condition is characterized by **hoarseness from infancy** due to deposition in the vocal cords and characteristic **beaded papules on the eyelids** (moniliform blepharosis). - Also known as **Urbach-Wiethe disease**, it is a rare autosomal recessive disorder resulting from mutations in the **ECM1 gene**, leading to abnormal deposition of hyaline material in various tissues. *Croup* - Croup typically presents with a **barking cough** and **stridor**, often following a viral upper respiratory infection. - It does not cause eyelid papules or chronic hoarseness from infancy, but rather acute respiratory distress. *Acrodermatitis enteropathica* - This is a rare autosomal recessive disorder of **zinc malabsorption**, leading to a classic triad of **dermatitis**, **diarrhea**, and **alopecia**. - It does not involve eyelid papules or hoarseness as primary features. *Congenital syphilis* - Congenital syphilis can cause a wide range of manifestations, including skin rashes, bone abnormalities, and rhinitis ("snuffles"), but eyelid papules and chronic hoarseness are not typical presenting features. - Diagnosis is usually confirmed by serological tests for syphilis.

Q: Which test is used to diagnose congenital syphilis in a newborn born to a syphilitic mother?

Detection of IgM. ***Detection of IgM*** - The presence of **IgM antibodies** in a newborn suggests active infection because maternal IgM does not cross the placenta. - This indicates the newborn's immune system has produced its own antibodies in response to *Treponema pallidum* infection. *Detection of IgG* - **Maternal IgG antibodies can cross the placenta**, so detecting IgG in a newborn does not differentiate between passive transfer from the mother and active newborn infection. - While total IgG might be elevated due to infection, specific IgM is a more reliable indicator of active congenital syphilis. *ZN staining* - **Ziehl-Neelsen (ZN) staining** is used to identify **acid-fast bacteria**, such as *Mycobacterium tuberculosis*, not spirochetes like *Treponema pallidum*. - *Treponema pallidum* is typically visualized using darkfield microscopy or silver stains due to its thin, helical shape. *FTA-ABS test* - The **Fluorescent Treponemal Antibody Absorption (FTA-ABS)** test detects specific antibodies against *Treponema pallidum* but primarily measures IgG, which can be maternally transferred. - While it confirms exposure, an IgM-specific FTA-ABS would be more definitive for congenital syphilis, but the general FTA-ABS test alone is not sufficient to diagnose active infection in a newborn.

Q: Which of the following is used to decrease the duration and severity of acute diarrhea?

Zn. ***Zn*** - **Zinc supplementation** has been shown to reduce the **duration** and **severity** of acute diarrhea, particularly in children in developing countries [1]. - It plays a crucial role in **immune function** and **intestinal integrity**, which helps in recovery from diarrheal episodes [1]. *Mg* - **Magnesium** is an essential mineral, but it is not directly used to decrease the duration or severity of acute diarrhea. - In fact, high doses of magnesium can act as a **laxative** and may worsen diarrhea. *Fe* - **Iron** is vital for red blood cell formation and oxygen transport, but it does not directly impact the duration or severity of acute diarrhea. - Iron supplementation is primarily used to treat **anemia**. *Ca* - **Calcium** is important for bone health and various metabolic processes, but it is not a primary intervention for reducing the duration or severity of acute diarrhea. - While sometimes used for mild digestive issues, it does not have the same evidence base as zinc for acute diarrhea.

Q: Most common site for bone marrow aspiration in neonates is -

Anteromedial tibia. ***Anteromedial tibia*** - The **anteromedial tibia** is the preferred site in neonates due to its relatively **large marrow cavity**, superficial location, and reduced risk of vital organ injury. - This site is easily accessible and provides a good yield of marrow cells, making it suitable for diagnostic purposes in newborns. *Anterior superior iliac crest* - While a common site for bone marrow aspiration in older children and adults, the **anterior superior iliac crest** can be more challenging and poses a greater risk in neonates due to their smaller bone structures. - The iliac crest offers less bony prominence and a thinner cortex in neonates, increasing the difficulty of the procedure and potential for sampling error. *Posterior superior iliac crest* - The **posterior superior iliac crest** is another common site in older children and adults but is generally avoided in neonates due to the difficulty in positioning and the risk of damaging vital structures in the vicinity. - It requires prone positioning and offers less superficial bone, making it a less practical and safe choice for neonates compared to the tibia. *Sternum* - **Sternal aspiration** is generally contraindicated in neonates and young children due to the thinness of the sternal bone and proximity to vital structures like the heart and great vessels. - There is a high risk of **perforation** of the sternum and injury to underlying organs, making this site unsafe for bone marrow aspiration in this age group.

Q: Which drug is not considered a mood stabilizer?

Imipramine. ***Imipramine*** - Imipramine is a **tricyclic antidepressant (TCA)**, primarily used to treat depression, not to stabilize mood in bipolar disorder. - TCAs can sometimes induce **mania** or hypomania in individuals with bipolar disorder, thus they are generally not used as monotherapy for mood stabilization. *Lithium* - **Lithium** is considered the gold standard and one of the oldest and most effective **mood stabilizers** for bipolar disorder. - It works by modulating **neurotransmitter systems** and second messenger pathways in the brain. *Lamotrigine* - **Lamotrigine** is an **anticonvulsant** medication that is also recognized as an effective **mood stabilizer**, particularly for preventing depressive episodes in bipolar disorder. - Its mechanism involves stabilizing neuronal membranes by blocking **voltage-gated sodium channels**. *Carbamazepine* - **Carbamazepine** is an **anticonvulsant** medication often used as a **mood stabilizer** for the treatment of acute manic and mixed episodes in bipolar disorder. - It works by reducing the excitability of nerve impulses through blocking **voltage-sensitive sodium channels**.

Q: Theory of human motivation was given by?

Abraham Maslow. ***Abraham Maslow*** - **Abraham Maslow** is renowned for his theory of **human motivation**, often depicted as **Maslow's Hierarchy of Needs**. - This theory posits that individuals are motivated to fulfill a hierarchy of needs, starting from basic physiological needs up to **self-actualization**. *Pavlov* - **Ivan Pavlov** is famous for his work on **classical conditioning**, particularly his experiments with dogs. - His contributions are primarily in the field of **learning theory**, not a comprehensive theory of human motivation. *Alois Alzheimer* - **Alois Alzheimer** was a psychiatrist and neuropathologist who first described the condition known as **Alzheimer's disease**. - His work focused on neurological disorders and neurodegenerative processes, not theories of human motivation. *Aaron Beck* - **Aaron Beck** is considered the father of **cognitive therapy** and is known for his work on the **cognitive triad** of depression. - While his theories relate to human thought and emotion, they do not constitute a broad theory of human motivation like Maslow's.

Q: Which of the following statements about lipoma is radiologically true?

Low attenuation on CT scan. ***Low attenuation on CT scan*** - Lipomas, being composed of **fat**, appear as areas of **low attenuation** (typically -50 to -150 Hounsfield Units) on computed tomography (CT) scans. - This low attenuation is a **key diagnostic characteristic** that helps differentiate lipomas from other soft tissue masses. *Hyperechoic on ultrasound* - Lipomas typically appear **isoechoic to hypoechoic** on ultrasound, not consistently hyperechoic. - They may have a thin echogenic capsule, but the internal contents are usually similar to or less echogenic than adjacent subcutaneous fat. *Hyperintense on fat-suppressed sequences* - This is **incorrect** - lipomas show **signal dropout** (become dark/hypointense) on fat-suppressed sequences (STIR, fat-sat T1/T2). - Signal suppression on fat-saturated sequences is actually a **diagnostic feature** confirming the fatty nature of the lesion. - Note: Lipomas ARE hyperintense on standard T1-weighted imaging due to fat content. *Hyper-intense on T2-weighted MRI* - Lipomas typically show **intermediate to slightly hyperintense signal** on T2-weighted MRI, but not markedly hyperintense like fluid. - They are less bright than fluid-filled structures or highly vascular lesions on T2-weighted sequences.

Question 1

Which bones form the floor of the nasal cavity in children?

Accepted Answer

Palatine process of the maxilla and horizontal plate of the palatine bone

Answer

Nasal bone and maxilla

Answer

Vomer and ethmoid

Answer

Nasal crest of maxilla and palatine process of maxilla

Question 2

Japanese encephalitis vaccine in routine schedule is given in how many doses -

Accepted Answer

Two doses (at 9-12 months and 15-18 months)

Answer

Single dose vaccine

Answer

Three doses 1 month apart followed by a booster if needed

Answer

Three doses with the second dose 1 month and 3rd dose 6 months after the first dose

Question 3

Reduced osmolarity ORS does not contain which of the following ions?

Accepted Answer

Lactate

Answer

Sodium

Answer

Potassium

Answer

Citrate

Question 4

What condition is suggested by eyelid papules and a hoarse cry in a child?

Accepted Answer

Lipoid proteinosis

Answer

Croup

Answer

Acrodermatitis enteropathica

Answer

Congenital syphilis

Question 5

Which test is used to diagnose congenital syphilis in a newborn born to a syphilitic mother?

Accepted Answer

Detection of IgM

Answer

Detection of IgG

Answer

ZN staining

Answer

FTA-ABS test

Question 6

Which of the following is used to decrease the duration and severity of acute diarrhea?

Accepted Answer

Zn

Answer

Mg

Answer

Fe

Answer

Ca

Question 7

Most common site for bone marrow aspiration in neonates is -

Accepted Answer

Anteromedial tibia

Answer

Anterior superior iliac crest

Answer

Posterior superior iliac crest

Answer

Sternum

Question 8

Which drug is not considered a mood stabilizer?

Accepted Answer

Imipramine

Answer

Lithium

Answer

Lamotrigine

Answer

Carbamazepine

Question 9

Theory of human motivation was given by?

Accepted Answer

Abraham Maslow

Answer

Pavlov

Answer

Aaron Beck

Answer

Alois Alzheimer

Question 10

Which of the following statements about lipoma is radiologically true?

Accepted Answer

Low attenuation on CT scan

Answer

Hyperechoic on ultrasound

Answer

Hyperintense on fat-suppressed sequences

Answer

Hyper-intense on T2-weighted MRI

NEET-PG 2015

Anatomy

Community Medicine

Dermatology

Microbiology

Pediatrics

Psychiatry

Radiology