NEET-PG 2013 Practice Questions

Q: The BEINGS Model of disease causation does not include which of the following factors?

Spiritual factors. ***Spiritual factors*** - The **BEINGS model** does not include \"Spiritual factors\" as one of its components. - The BEINGS acronym stands for: **B**iological, **E**nvironmental, **I**mmunological, **N**utritional, **G**enetic, and **S**ocial factors. - While spirituality can influence health outcomes, it is not a formal component of this epidemiological model. *Religious factors* - Religious factors, like spiritual factors, are also not explicitly part of the BEINGS model. - However, religious practices and beliefs may be considered as part of **social factors** (the \"S\" in BEINGS) in some contexts. - This option is less clearly excluded than spiritual factors. *Social factors* - The \"**S**\" in BEINGS specifically stands for **Social factors**, not spiritual factors. - Social factors include community networks, socioeconomic status, cultural practices, and social support systems. - These are well-established determinants of health and disease causation. *Nutritional factors* - The \"**N**\" in BEINGS stands for **Nutritional factors**. - Nutrition plays a critical role in disease causation, affecting immunity, growth, and susceptibility to various diseases. - Deficiencies or excesses in nutrition can lead to a wide range of health problems.

Q: Which color indicates the highest priority in triage?

Red. ***Correct: Red*** - The color **red** is universally used in triage systems to designate the **highest priority** patients, indicating immediate threats to life or limb. - Patients triaged as red require **immediate intervention** and transport to maximize their chances of survival. *Incorrect: Yellow* - **Yellow** indicates a **delayed priority**, meaning patients have serious injuries but their conditions are not immediately life-threatening. - These patients can typically wait for a few hours before receiving definitive medical care. *Incorrect: Green* - **Green** is assigned to patients with **minor injuries** or illnesses that are unlikely to deteriorate over time. - They are considered walking wounded and can often wait for an extended period or be treated with minimal resources. *Incorrect: Black* - **Black** signifies **deceased** or expectant patients, indicating those whose injuries are so severe that survival is unlikely given the available resources. - Resources are typically withheld from these patients to prioritize those with a higher chance of survival.

Q: What is the drug of choice for bleeding oesophageal varices?

Octreotide. ***Octreotide*** - **Octreotide** is an analogue of **somatostatin** that reduces splanchnic blood flow and portal pressure, thereby decreasing bleeding from esophageal varices. - It is often used in the acute management of **bleeding esophageal varices** due to its rapid onset of action and favorable safety profile. *Ethanolamine oleate* - **Ethanolamine oleate** is a **sclerosing agent** used for endoscopic sclerotherapy of esophageal varices, not typically as the initial drug of choice for acute bleeding [1]. - It acts by causing inflammation and fibrosis of the varices, which can be effective but carries risks such as **esophageal ulceration** or perforation. *Propranolol* - **Propranolol** is a **non-selective beta-blocker** used for the prophylactic prevention of variceal bleeding, not for acute management of active bleeding. - It works by reducing portal venous pressure by decreasing cardiac output and splanchnic vasoconstriction. *Phytonadione* - **Phytonadione** (vitamin K1) is used to reverse **coumarin anticoagulant effects** or to treat **vitamin K deficiency**, which can contribute to bleeding but is not a direct treatment for variceal bleeding itself. - It helps in the synthesis of **coagulation factors II, VII, IX, and X**, thereby improving clotting.

Q: Which of the following is a cause of Valley fever (desert rheumatism)?

Coccidioides. ***Coccidioides*** - **Valley fever**, or desert rheumatism, is caused by infection with the dimorphic fungus **Coccidioides**, primarily **Coccidioides immitis** and **Coccidioides posadasii**. - This fungus is endemic to arid and semi-arid regions, especially the **southwestern United States** and parts of Central and South America. *Sporothrix* - **Sporothrix schenckii** causes sporotrichosis, a chronic fungal infection typically involving the skin, subcutaneous tissue, and adjacent lymphatics, often through skin trauma. - It does not cause Valley fever. *Cladosporium* - **Cladosporium** species are ubiquitous molds commonly found in outdoor and indoor environments, often associated with allergic reactions and occasionally superficial infections. - They are not a cause of Valley fever. *Phialophora* - **Phialophora** species are dematiaceous fungi that can cause phaeohyphomycosis, chromoblastomycosis, and eumycetoma, which are subcutaneous or systemic fungal infections. - They are not associated with Valley fever.

Q: A 4 year old child presents with acute watery diarrhea and abdominal cramps. Stool microscopy reveals trophozoites with falling leaf motility. What is the etiological agent?

Giardia lamblia. **Giardia lamblia** - The presence of **trophozoites** with characteristic **falling leaf motility** in stool microscopy is pathognomonic for **Giardia lamblia** infection. - **Giardiasis** commonly causes **acute watery diarrhea** and **abdominal cramps** in children, often acquired through contaminated water or food. *Entamoeba histolytica* - **Entamoeba histolytica** causes **amoebic dysentery**, characterized by bloody diarrhea, unlike the watery diarrhea described. - Its trophozoites exhibit **directional motility** with pseudopods and may contain ingested red blood cells, not falling leaf motility. *Trichomonas tenax* - **Trichomonas tenax** is found in the **oral cavity** and is not associated with intestinal infections or diarrhea. - Its typical habitat and clinical presentation are entirely different from the symptoms described. *Balantidium coli* - **Balantidium coli** is a large, ciliated protozoan whose trophozoites have a **distinctive kidney-shaped macronucleus** and rotary motility with cilia. - It causes **balantidiasis**, which can range from asymptomatic to dysentery, but its trophozoite morphology and motility are distinct from falling leaf.

Q: All are non-sporing anaerobes of medical importance except which of the following?

Clostridia. ***Clostridia*** - This genus is characterized by its ability to form **spores**, which are highly resistant structures allowing survival in adverse conditions. - Examples include *Clostridium difficile*, *Clostridium tetani*, and *Clostridium botulinum*, all of which are important human pathogens. *Actinomyces* - *Actinomyces* are **non-sporing, Gram-positive, anaerobic rods** that cause chronic, granulomatous infections, often forming sinus tracts. - They are known for producing characteristic **"sulfur granules"** in pus. *Bacteroides* - *Bacteroides* are **non-sporing, Gram-negative, anaerobic rods** that are a major component of the normal human gut flora. - They are frequently involved in **intra-abdominal infections** and abscess formation. *Fusobacterium* - *Fusobacterium* species are **non-sporing, Gram-negative, fusiform-shaped anaerobic rods**. - They are common in the **oral cavity** and can cause infections such as Vincent's angina and Lemierre's syndrome.

Q: Which of the following is an intermediate level disinfectant?

Hypochlorite. ***Hypochlorite*** - **Hypochlorite** (e.g., sodium hypochlorite, bleach) is an effective **intermediate-level disinfectant** commonly used for surface disinfection and water purification. - It works by **oxidizing cellular components** and disrupting membrane function in microorganisms, effective against a wide range of bacteria, viruses, and some fungi. *2% glutaraldehyde* - **2% glutaraldehyde** is a **high-level disinfectant** and **sterilant** often used for heat-sensitive medical equipment like endoscopes. - It is effective against bacterial spores, mycobacteria, fungi, and viruses, which exceeds the scope of intermediate-level disinfection. *Ethylene oxide* - **Ethylene oxide** is a **gaseous sterilant** used for heat-sensitive and moisture-sensitive medical devices, making it a high-level modality. - It works by **alkylating proteins and nucleic acids**, effectively killing all forms of microbial life, including spores. *None of the options* - This option is incorrect because **Hypochlorite** is indeed an intermediate-level disinfectant. - The classification of disinfectants is based on their ability to kill different types of microorganisms, with hypochlorite falling squarely into the intermediate category.

Q: Which of the following drugs has not been withdrawn from the Indian market for safety reasons?

Cotrimoxazole. ### Cotrimoxazole - Cotrimoxazole, a combination of **trimethoprim and sulfamethoxazole**, remains a widely used and available antibiotic in India [1], [2]. - It treats various bacterial infections, including **urinary tract infections** and respiratory infections, and has not been withdrawn for safety reasons [1]. ### Gatifloxacin - **Gatifloxacin** was withdrawn from the Indian market due to concerns about **severe glycemic disturbances**, including both hypo- and hyperglycemia. - These side effects posed significant risks, especially in patients with diabetes or those predisposed to blood sugar fluctuations. ### Rofecoxib - **Rofecoxib**, an NSAID, was withdrawn globally, including from India, due to an increased risk of **cardiovascular events** such as heart attack and stroke. - Its selective inhibition of COX-2 was found to disturb the balance of prostaglandins, leading to adverse cardiovascular outcomes. ### Phenformin - **Phenformin**, an oral antidiabetic drug, was withdrawn from the Indian market due to its association with a high incidence of **lactic acidosis**, a severe and often fatal metabolic complication. - This serious side effect made its risk-benefit profile unacceptable for continued use.

Q: Which of the following is an antitussive opioid?

Ethylmorphine. ***Ethylmorphine*** - **Ethylmorphine** (also known as dionin) is an opioid derivative with significant **antitussive properties**, meaning it suppresses coughing. - It works by acting on opioid receptors in the **medulla oblongata**, reducing the cough reflex. *Pethidine* - **Pethidine** (also known as meperidine) is a synthetic opioid primarily used for **moderate to severe pain relief**. - While it has some central nervous system effects, its main therapeutic use is as an **analgesic**, not an antitussive. *Methadone* - **Methadone** is a synthetic opioid used for treating **opioid dependence** and for **chronic severe pain**. - Its main application is in addiction treatment and pain management, not specifically as a cough suppressant. *Buprenorphine* - **Buprenorphine** is a **partial opioid agonist** used for pain management and **opioid dependence**. - It has a high affinity for opioid receptors but produces a limited effect, making it less likely to be used solely as an antitussive and more for its analgesic or anti-addictive properties.

Q: What is the role of Anandamide in the human body?

Cannabinoid neurotransmitter. ***Cannabinoid neurotransmitter*** - **Anandamide** is an **endogenous cannabinoid neurotransmitter** that binds to **CB1** and **CB2 receptors**. - It plays a role in **pain modulation**, **appetite stimulation**, and **memory regulation**. *Opioid* - **Opioids** bind to **opioid receptors** (mu, delta, kappa) and are known for their **analgesic** and **euphoric effects**. - Examples include **morphine** and **endorphins**, which are chemically distinct from anandamide and have different receptor targets. *CK 1 antagonist* - This option refers to a **cholecystokinin 1 (CCK1) receptor antagonist**, which would block the effects of **CCK**. - **CCK** is a hormone involved in **digestion** and **satiety**, and its role is unrelated to anandamide. *D2 blocker* - A **D2 blocker** is an agent that antagonizes the **dopamine D2 receptor**. - These are typically **antipsychotic medications** that modulate **dopamine pathways** in the brain, unrelated to the function of anandamide.

Question 1

The BEINGS Model of disease causation does not include which of the following factors?

Accepted Answer

Spiritual factors

Answer

Religious factors

Answer

Social factors

Answer

Nutritional factors

Question 2

Which color indicates the highest priority in triage?

Accepted Answer

Red

Answer

Yellow

Answer

Green

Answer

Black

Question 3

What is the drug of choice for bleeding oesophageal varices?

Accepted Answer

Octreotide

Answer

Ethanolamine oleate

Answer

Propanolol

Answer

Phytonadione

Question 4

Which of the following is a cause of Valley fever (desert rheumatism)?

Accepted Answer

Coccidioides

Answer

Sporothrix

Answer

Cladosporium

Answer

Phialophora

Question 5

A 4 year old child presents with acute watery diarrhea and abdominal cramps. Stool microscopy reveals trophozoites with falling leaf motility. What is the etiological agent?

Accepted Answer

Giardia lamblia

Answer

Trichomonas tenax

Answer

Balantidium coli

Answer

Entamoeba histolytica

Question 6

All are non-sporing anaerobes of medical importance except which of the following?

Accepted Answer

Clostridia

Answer

Bacteroides

Answer

Fusobacterium

Answer

Actinomyces

Question 7

Which of the following is an intermediate level disinfectant?

Accepted Answer

Hypochlorite

Answer

Ethylene oxide

Answer

2% glutaraldehyde

Answer

None of the options

Question 8

Which of the following drugs has not been withdrawn from the Indian market for safety reasons?

Accepted Answer

Cotrimoxazole

Answer

Gatifloxacin

Answer

Phenformin

Answer

Rofecoxib

Question 9

Which of the following is an antitussive opioid?

Accepted Answer

Ethylmorphine

Answer

Pethidine

Answer

Methadone

Answer

Buprenorphine

Question 10

What is the role of Anandamide in the human body?

Accepted Answer

Cannabinoid neurotransmitter

Answer

Opioid

Answer

D2 blocker

Answer

CCK1 antagonist

NEET-PG 2013

Community Medicine

Internal Medicine

Microbiology

Pharmacology

Physiology