Hematopathology — Flashcards

Flashcard 361: _____ is an epigenomic regulatory gene mutated in 90% of follicular lymphomas

Answer: MLL2

Flashcard 362: t(14;16), del 17p, and t(4;14) in multiple myeloma is associated with a _____ prognosis

Answer: poor

Flashcard 363: The optimum time for performing leukoreduction is before _____

Answer: storage

Flashcard 364: In touch preparations of Extranodal NK/T-Cell Lymphoma, large _____philic granules are seen in the cytoplasm of the tumor cells

Answer: azuro

Flashcard 365: Which variant of Reed-Sternberg cells is seen with lymphocyte depleted subtype of Hodgkin's lymphoma?_____

Answer: reticular variant

Flashcard 366: Blasts usually make up _____% of the circulating cells in accelerated phase of chronic myeloid leukemia

Answer: 10-19

Flashcard 367: Hereditary _____ is a type of hemolytic anemia causing extreme variation in RBC size and shape.

Answer: pyropoikilocytosis

Flashcard 368: Hematopoetic presentation of acute radiation syndrome is marked by _____

Answer: aplastic anemia

Flashcard 369: What name is given to the plasma cells seen in myeloma (typically IgA) that contain immunoglobulin within dilated cisternae of the endoplasmic reticulum?

Answer: Thesaurocytes

Extra: Thesaurocytes are a morphological variant of plasma cells, typically associated with IgA myeloma. They are characterized by the accumulation of immunoglobulin within dilated cisternae of the rough endoplasmic reticulum (RER), giving the cell a 'storage cell' appearance.

Flashcard 370: _____ lymphadenitis is also known as histiocytic necrotizing lymphadenitis.

Answer: Kikuchi's